Assessment of fetal-maternal haemorrhage in mothers with hereditary persistence of fetal haemoglobin.
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چکیده
منابع مشابه
Assessment of fetal-maternal haemorrhage in mothers with hereditary persistence of fetal haemoglobin.
Kleihauer examination of peripheral blood cannot be used reliably to detect transplacental fetal-maternal haemorrhage in mothers with hereditary persistence of fetal haemoglobin (HPFH). In Rh(D) negative pregnancies diagnostic confusion with a large fetal-maternal haemorrhage could result in the administration of inappropriately excessive amounts of anti-D immunoglobulin, and the inability to d...
متن کاملHereditary Persistence of Fetal Hemoglobin in Greece
By PHAEDON FESSAS AND GEORGE STAMATOYANNOPOULOS H EREDITARY PERSISTENCE of fetal hemoglobin was described in a Greek family in 1961 and included the combination of this anomaly with aand with -thalassemia.1’2 Since then, further cases or families have been observed in Greece, two of which have been reported in whole or in part in Greek medical literature.3’4 This material now permits an adequat...
متن کاملFeto-maternal haemorrhage assessment in a woman with a large population of red blood cells containing fetal haemoglobin.
BACKGROUND FMH quantification is necessary to calculate an individual dose of prophylactic anti-RhD immunoglobulin and to diagnose fetal anaemia causes. We encountered a healthy woman with a numerous RBCs containing fetal haemoglobin (HbF). AIMS To investigate the cause of this sign and the correct evaluation of fetal RBCs in maternal circulation. MATERIALS AND METHODS Patients samples and ...
متن کاملRetinal changes in sickle cell/hereditary persistence of fetal haemoglobin syndrome.
We describe for the first time retinal changes in sickle cell/hereditary persistence of fetal haemoglobin syndrome, which is a rare and benign disorder. The changes are qualitatively similar to retinal disease seen with sickle haemoglobin and sickle C haemoglobin, but are mild.
متن کاملBalanced globin chain synthesis in hereditary persistence of fetal hemoglobin.
In two black families with the hereditary persistence of fetal hemoglobin (HPFH) gene there are eight A-F heterozygotes and two double heterozygotes for sickle cell trait and HPFH. These patients are clinically asymptomatic and have homogeneous acid elution smears. Measurement of globin chain synthesis in peripheral blood demonstrates balanced production of a alpha and non-alpha (beta plus gamm...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1990
ISSN: 0021-9746
DOI: 10.1136/jcp.43.9.728